ABOUT US

Our Story

Clarapath was founded in 2014 as a spin-off of Dr. Partha Mitra's research on high-throughput neuroanatomy at Cold Spring Harbor Labs. In order to facilitate whole-brain digital neuroanatomy research, Dr. Mitra was processing hundreds of thousands of tissue samples using the tape-transfer method for high-quality microtomy (cutting tissue into micrometer-thin sections for further analysis). The tape-transfer method was originally developed to facilitate the transport of only frozen tissue sections to glass slides for clinical application of anatomic pathology. Historically, tape-transfer has not been used for paraffin wax tissue processing.

 

Based on this experience, Dr. Mitra had the idea to use the tape-transfer method as a foundation to develop a fully automated microtomy system.  The device, named SectionStar, takes paraffin tissue blocks as inputs and provides glass slides with sliced tissue as outputs. The device is being developed in close concert with Northwell Health and the Northwell Health Laboratory. SectionStar will be transformative toward improving patient care, decreasing costs, and enhancing the quality and consistency of tissue preparation. The SectionStar further automates the last remaining manual process in histopathology.  

Automating microtomy shouldn't take 100 years

The last remaining manual step in tissue processing

Fixation
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AUTOMATED
Processing
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AUTOMATED
Embedding
AUTOMATED
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Microtomy
MANUAL
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Staining
AUTOMATED
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Today's histology labs are rife with operational & quality challenges

Our journey to enhance pathology started with a operational shortage

NOT SCALABLE

Microtomy is a bottleneck for increased lab throughput with a 1:1 labor-to-output ratio

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INEFFICIENT

Biopsy turnaround time is often delayed and labs can't keep up with the demand 

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HIGHLY SUBJECTIVE

Quality is heavily influenced by the operator and there is a lack of a "gold standard" in terms of quality of slide consistency

EXPENSIVE

Skilled human labor is a major lab expense and labor supply is on the decline - vacancy rates are approaching 10% for histotechnologists

HARMFUL

Histology is a central element of practicing medicine and approximately 6% of detected errors lead to patient harm

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PRONE TO ERROR

Traditional water bath leads to tearing, folding & "float" and 99% of errors are preventable human errors

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Meet The Team

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Dr. Partha Mitra, Ph.D.

Founder & Chief Scientific Advisor

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Eric Feinstein

Chief Executive Officer

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Baris Yagci, Ph.D.

R&D Director

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Jay Sewkarran

Director of Information Technology

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Kavita Sethi

HR & Finance

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Matthew Claster

Corporate Development & Strategy

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Robert Shusko

Engineering Project Manager 

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Dmitry Khavulya

Principal Software Engineer

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Jerry Pinto, Ph.D.

Principal Materials Engineer

Weston Smith

Mechanical Engineer

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Jonathan Gardi, Ph.D.

User Interface Software Engineer

Steven L. Smith, Ph.D.

Principal Optical Engineer

Maliha Momtaj

Operations & Special Projects

Board of Directors

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Dr. Partha Mitra, Ph.D.

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Sherry Liu

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Charles Cantor, Ph.D.

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David Eigen

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Robert Stallone

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James Crawford, MD, Ph.D.

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Michael Shelanski, MD, Ph.D.

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Clinical & Scientific Advisors

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James Crawford, MD, Ph.D.

  • SVP, Lab Services, Northwell Health

  • Chairman, Department of Pathology, Zucker School of Medicine

  • Professor, Feinstein Institute for Medical Research

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Robert Stallone

  • VP of Lab Services, Northwell Health

  • Founding Member, COMPASS Group

  • Previously Roche Diagnostics, Sysmex Corporation, UBS

  • Member of the AACC & CLMA

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Daniel T. Barry, MD, Ph.D.

  • NASA Astronaut, Retired

  • Founder & President, Denbar Robotics

  • Co-Founder, FellowAI

  • Co-Chair of Faculty of AI, Singularity University

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David Kleinfeld

  • Professor, University of California

  • Principal Investigator, David Kleinfeld Laboratory

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Patrik Dahlen, Ph.D.

  • Biochemistry expert

  • Former CEO, Dako, Chempac, Neurosearch and Immunodiagnostic Systems

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Michael Shelanski, MD, Ph.D.

  • Former Chairman, Department of Pathology, Columbia University

  • Sr. Vice Dean, Research, Columbia University

  • Co-Director, Taub Institute

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Charles Cantor, Ph.D.

  • Director for the Center of Advanced Biotechnology at Boston University

  • Previously CSO of Sequenom 

  • Co-founder of Retrope

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Yukako Yagi, Ph.D.

  • Director, Pathology Imaging Center, Mass General Hospital

  • Assistant Professor Pathology, Harvard Medical School